Vincristine Sulphate Injection 2mg For Dogs & Cats 1mL x 5

• Vincristine, also known as Oncovin, belongs to a group of medications known as vinca alkaloids and is obtained from the plant Cantharanthus roseus. It is often used for dogs and cats to treat malignant cancers of the lymphoid and blood systems.
• The drug is commonly used in the treatment of cancer. One of the hallmarks of cancer is the speed at which cancer cells divide.
• Vincristine will bind to the proteins of actively dividing cells, preventing cell division and resulting in cell death.
• Since cancer cells tend to divide rapidly, the drug will primarily effect these cells. Unfortunately, certain other body cells also divide rapidly, such a hair and gastrointestinal lining cells, resulting in effects on these sites of the body as well.
• Vincristine has been shown to induce the release of already existing platelets from the bone marrow in dogs but the exact way this accomplished is not fully understood.
• Vincristine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
• This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug.

Uses

• Vincristine is used to treat malignant cancers of the lymphoid and blood systems. It has also been used to treat hemangiosarcoma and transmissible venereal tumor.
• Vincristine is also used to treat immune-mediated platelet disorders.

Precautions and Side Effects

• While generally safe and effective when prescribed by a veterinarian, vincristine can cause side effects in some animals. As with other cancer treating drugs, vincristine is a strong drug and the potential side effects can be serious.
• Vincristine should not be used in animals with known hypersensitivity or allergy to the drug.
• Vincristine should be avoided in animals with liver disease, low white blood cell counts, active infections or disease of the nervous system.
• Vincristine may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with vincristine.
• Toxic effects of vincristine can affect the nervous system, resulting in weakness, collapse or seizure.
• This drug has been shown to suppress the immune system in some animals.
• Vincristine may cause hair loss, vomiting, nausea or diarrhea.
• This medication should only be given intravenous. If injected outside the vein, significant inflammation, including skin necrosis or sloughing, may occur.